再生医療 - 幹細胞療法

Medical Services

Medical Services

Regenerative Medicine

Regenerative medicine is a field of treatment in which a patient’s own cells—or qualified donor cells—are cultured and used to repair or regenerate tissues and organs that have been damaged or lost.

There are three primary approaches:

1 Culturing and re-implanting a patient’s own healthy cells 2 Using cells obtained from a donor 3 Transplanting artificially engineered tissues or organs

  • At The cell clinic, our adipose-derived stem cell therapy falls under Method 1—culturing and returning your own cells to the body.
    While many regenerative techniques are still under clinical study, several applications such as burn treatment and cartilage regeneration are already in clinical use and have significantly improved patients’ quality of life.
    Because this approach addresses the underlying cause of disease or injury, regenerative medicine is increasingly recognized as a fundamental, root-cause treatment that supports pain relief, functional recovery, and return to daily activities.

Commitment to Safety

Japan’s Act on Ensuring the Safety of Regenerative Medicine (enforced November 2014) defines facility standards and cell-processing regulations.
At our clinic, we adhere to strict quality control, contamination prevention, and long-term monitoring to ensure patient safety and treatment reliability.

Considering Treatment

The most suitable regenerative approach varies depending on each patient’s condition, medical history, and goals.
We encourage you to consult with our physicians to determine the treatment plan that best fits your needs.

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幹細胞

STEM CELL THERAPY

Stem Cell Therapy

From extraction to administration — all within our in-house CPF system for precision and safety.

Stem cell therapy is an advanced, body-friendly regenerative treatment that harnesses the human body’s innate ability to repair itself.It aims to regenerate and restore damaged cells or tissues caused by aging, disease, or lifestyle factors, supporting functional recovery.

At The cell clinic, adipose-derived stem cells are cultured in our on-site facility for approximately three weeks.Only after confirming safety and quality through genome analysis are the cells administered.We use exclusively human-derived serum, ensuring biocompatibility and minimizing the risk of immune rejection.This enables fully personalized treatment tailored to each patient’s condition and stage of disease.

What Are Stem Cells

Our bodies are naturally equipped with the ability to repair and regenerate.
The source of that ability lies in stem cells.
Stem cells possess two unique characteristics that distinguish them from other cells.

01. Self-Renewal
(The ability to replicate cells with the same properties)

自己複製能の図解

Stem cells have the ability to divide and produce identical copies of themselves — a property known as self-renewal.This mechanism allows the body to maintain its cell population over many years, replenishing lost or damaged tissues.

02. Multipotency
(The ability to transform into various cell types)

多分化能の図解

Another remarkable feature of stem cells is their multipotency — the potential to differentiate into diverse cell types such as skin, muscle, nerve, and vascular cells.By transforming according to the body’s needs, stem cells play a vital role in repairing damaged tissues.

03.Stem Cell Functions

[Homing Effect]

Stem cells naturally migrate toward damaged or degenerated tissues — a process known as the homing effect.When injured or inflamed tissues release distress signals, stem cells travel through the bloodstream to the affected site, where they differentiate into specific cells and assist in tissue repair.

[Paracrine Effect]

Stem cells secrete bioactive substances that stimulate nearby cells to repair and regenerate.This process, called the paracrine effect, involves the release of growth factors and cytokines that promote cell proliferation and enhance cellular activity, supporting regeneration especially around the damaged area.

[Endocrine Effect]

In addition to local repair, stem cells influence distant organs through the endocrine effect.Growth factors and cytokines secreted by stem cells circulate through the bloodstream, acting like hormones to modulate cell function in remote tissues, contributing to whole-body balance and systemic recovery.

04.Expected Benefits

[Main Target Conditions]

・Type 2 diabetes
・Chronic pain (neuropathic / inflammatory), stiffness, and long-lasting joint pain
・Autoimmune diseases (e.g., atopic dermatitis, rheumatoid arthritis)
・Joint disorders (e.g., knee osteoarthritis, rotator cuff injury), tendon or ligament damage
・Reduction of wrinkles and sagging due to aging
・Liver diseases (e.g., cirrhosis)
・Post-stroke functional recovery
・Neurological disorders such as Parkinson’s disease
・General wellness enhancement and preventive rejuvenation

Note: Chronic pain and joint disorders are among the key conditions treated at our clinic.

[Reported Secondary Improvements]

・Improved sleep quality
・Enhanced concentration and memory
・Emotional stability and stress resilience
・Clearer vision and slower progression of presbyopia
・Brighter, firmer, more youthful-looking skin
・Increased hair volume and reduction in gray hair

05.Treatment Process

  1. 1 Consultation (medical history and medications review)
  2. 2 Fat Extraction (local anesthesia, short procedure)
  3. 3 Cultivation (4–5 weeks)
  4. 4 Quality and Safety Verification
  5. 5 Administration (IV infusion or local injection)
    — same-day treatment, followed by observation and discharge

06.Safety Management

・ Sterile operation and lot control within our in-house CPF (Cell Processing Facility)
・ Dosage design and suitability evaluation by physicians
・ Established standardized procedures for adverse event response

[Side Effects / Precautions]

Mild pain or bruising at the injection site, rare fever, or allergic reactions.Please consult your physician beforehand if you are pregnant, breastfeeding, or have a serious underlying medical condition.

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培養上清

CULTURE SUPERNATANT TREATMENT

Conditioned Media Therapy

A gentle, cell-signaling approach to restoration and wellness.

Conditioned media is the nutrient-rich supernatant obtained during the culture of stem cells.It contains cytokines, growth factors, and exosomes—bioactive molecules that act as messengers between cells.
Depending on the patient’s goals, treatment may be administered as an intravenous infusion for systemic rejuvenation, or localized injection to the scalp, skin, or joints for targeted repair.At The cell clinic, we use only medical-grade conditioned media produced under strict laboratory conditions, ensuring the highest standards of quality and safety.It is ideal for comprehensive wellness, beauty enhancement, fatigue recovery, and anti-aging care, customized to each patient’s needs.

Stem Cell Conditioned Media

Stem cell conditioned media refers to the supernatant fluid obtained during the process of culturing human stem cells.It is rich in bioactive substances secreted by the stem cells themselves, including growth factors, cytokines (※1), and exosomes (※2).These components help activate aging tissues and promote cellular repair and regeneration.

Stem cell conditioned media have shown great promise in regenerative medicine, aesthetic medicine, and the treatment of chronic diseases.Research suggests that it may contribute to skin rejuvenation, tissue regeneration, and the suppression of inflammation.In this way, conditioned media allow patients to benefit safely and efficiently from the regenerative potential of stem cells—without requiring direct cell transplantation.

幹細胞培養上清液の説明図

(※1) Cytokines – Signaling molecules responsible for intercellular communication that regulate immune balance, inflammation control, and tissue repair.
(※2) Exosomes – Microscopic vesicles that transmit information between cells, enhancing cellular activation and repair.

Effects of Conditioned Media Therapy

Because stem cell conditioned media contain a large number of active substances—such as growth factors, cytokines, and exosomes—the therapy is expected to promote fatigue recovery, delay aging, improve skin texture, and relieve joint pain.
It is also reported to be effective for stiffness in the shoulders and lower back.

[Aesthetic Effects]

Promotes skin cell turnover, improving wrinkles and pigmentation
Stimulates collagen, elastin, and hyaluronic acid production to enhance firmness and elasticity
Supports hair restoration and growth

[Health Effects]

Promotes tissue repair and regeneration
Boosts immune function
Reduces inflammation through anti-inflammatory action
Relieves joint and nerve pain
Helps prevent and improve lifestyle-related diseases

Applications include:
Tissue regeneration / Repair enhancement / Anti-inflammatory action / Skin rejuvenation (wrinkle & sagging improvement) / Immune modulation / AGA (male-pattern baldness) / Neuroprotection and regeneration / Metabolic improvement / Wound healing / Chronic pain / Peripheral neuropathy / Arthritis & tendon injury / Whitening effect / Atopic dermatitis / Acne scars / Vitiligo / Myocardial infarction & angina / Arteriosclerosis / Peripheral arterial disease / Liver dysfunction (hepatitis, cirrhosis) / Diabetes / Chronic renal failure / ED treatment / Stroke & brain injury / Parkinson’s disease / Alzheimer’s disease / Spinal cord injury / ALS (amyotrophic lateral sclerosis) / Multiple sclerosis / Joint pain relief / Pulmonary emphysema & fibrosis / COPD / Menopausal disorder / Erectile dysfunction / Post–COVID-19 syndrome / Autoimmune diseases (e.g., rheumatoid arthritis)

Administration Methods

Stem cell conditioned media contain abundant secreted components—cytokines, growth factors, and exosomes.
Depending on the patient’s condition and purpose, The cell clinic provides several administration methods:

1.

Intravenous Infusion (IV)

The most common method. Conditioned media are administered directly into a vein to circulate throughout the body.This approach is ideal for improving overall vitality, immune modulation, beauty, and anti-aging.It is known for both its immediacy and long-lasting benefits.

2.

Local Injection

Conditioned media are injected directly into the affected areas—such as joints, muscles, or skin.This method is suitable for relieving joint pain (shoulders, knees), treating sports injuries or inflammation,and promoting skin regeneration in aesthetic applications that target specific areas.

3.

Intranasal Administration

This method delivers the active components through the nasal cavity, allowing them to act directly on the brain.By traveling via the olfactory nerve, the ingredients may help regulate the autonomic nervous system,support cognitive function, and improve sleep quality.

Note:Stem cell conditioned media therapy is classified as advanced private medical care (self-funded treatment) and is not covered by public insurance.

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美容治療

INFUSION THERAPY

Infusion Therapy

“Revealing your natural beauty from within.”

Aging is not a negative process—it is a reflection of life’s journey.What truly matters is nurturing one’s own beauty naturally and gracefully.At The cell clinic, our aesthetic infusion therapies are based on the science of regenerative medicine.We work to awaken your skin’s innate vitality and support beauty that radiates from within.
Rather than simply concealing wrinkles, sagging, or dullness, our goal is to address these aging signs at their root.We tailor each treatment to your skin’s unique condition, offering medically supervised care that ensures both safety and exceptional results.Experience the confidence and refinement that only a medical aesthetic approach can provide.

Stem Cell Conditioned Media Infusion

The Stem Cell Conditioned Media Infusion is rich in growth factors and bioactive proteins secreted by stem cells.Administered intravenously, it circulates throughout the entire body, helping dormant cells awaken and recover their natural function.This advanced anti-aging therapy promotes systemic regeneration—from skin revitalization and immune enhancement to fatigue recovery—supporting youthful beauty from within.

[Expected Benefits]
Immune enhancement / Fatigue recovery / Whole-body rejuvenation / Skin revitalization / Texture improvement / Anti-aging / Hair growth and scalp support

STANDARD
¥ 66,000 (tax included)

An accessible plan ideal for first-time patients or those seeking routine rejuvenation.Promotes skin turnover, relieves fatigue, and boosts immune strength for balanced, everyday wellness and graceful aging.

PREMIUM
¥ 220,000 (tax included)

A high-intensity program for those seeking deeper and longer-lasting effects.Uses highly concentrated conditioned media for enhanced regeneration, greater skin elasticity, chronic fatigue recovery, and improved immune function.

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幹細胞培養上清液注入治療

SKIN REGENERATION TREATMENTS

Skin Regeneration Treatments

Authentic skin rejuvenation — delivering real radiance and resilience.
This advanced treatment directly injects stem cell conditioned media into the skin. Rich in growth factors and nutritional proteins, it activates skin cells and stimulates collagen production, resulting in firmer, more supple, and luminous skin. It effectively addresses concerns such as dark circles, sagging, uneven texture, enlarged pores, acne scars, and dullness. By enhancing the skin’s natural healing ability, it also strengthens the barrier function, protecting against external stressors. This therapy is ideal for those seeking natural rejuvenation, noticeable improvement in skin quality, and minimal downtime—delivering discreet yet remarkable results.

[Expected Benefits] Improved firmness and elasticity / Reduction of wrinkles and sagging / Pore refinement / Smoother texture / Brighter, more even skin tone

Skin Rejuvenation Injection
¥ 110,000 (tax included)

[Expected Benefits]

Firmness and elasticity / wrinkles / sagging / pores / Improves acne scars / blemishes / and dullness

Direct injection of stem cell conditioned media for deep rejuvenation and collagen stimulation.Ideal for enhancing texture, elasticity, and radiance with minimal downtime.

Stem Cell Conditioned Media Meso Therapy
¥ 110,000 (tax included)

[Expected Benefits]

Whitening and brightening / Pore tightening / Hair loss prevention / Post-procedure recovery support

This mesotherapy activates hair follicle stem cells with growth and nutritional factors to stimulate hair growth and scalp health. It suppresses hair loss, improves blood circulation, and provides anti-inflammatory effects to the scalp. Effective for AGA, FAGA, and alopecia areata, this treatment supports hair volume restoration and rejuvenation. Injection methods and concentrations are customized according to the treatment area and patient goals.

Male Rejuvenation Treatment
¥ 110,000 (tax included)

[Expected Benefits]

Improved erectile function / Tissue regeneration / Enhanced sexual satisfaction / Increased blood flow

A regenerative approach to improving male function.Growth factors promote angiogenesis and enhance circulation, supporting recovery from fatigue and preventing age-related decline.This treatment aims for natural improvement and functional enhancement, with plans adjusted for dosage, concentration, and individual goals

幹細胞培養上清液注入治療
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背景

An evolution of the dermapen
— Microneedle RF System

POTENZA is a next-generation treatment that uses RF (radio frequency) energy and microneedle technology to improve wrinkles, enlarged pores, acne scars, active acne, and melasma.
Also known as an “advanced dermapen,” this dual-action approach stimulates collagen production for firmer, smoother, and more youthful skin.

[Expected Benefits]

Improves sagging / Tightens skin / Enhances firmness and elasticity

Using two types of diamond-tip RF applicators, this treatment achieves remarkable lifting and tightening effects with minimal discomfort and noticeable results even after a single session.

POTENZA システム
  • ・300 shots ・・・ ¥ 19,800 (tax included)

  • ・500 shots ・・・ ¥ 33,000 (tax included)

[Expected Benefits]

Acne scars / Pores / Fine lines / Redness

By combining microneedle and RF technology, POTENZA delivers energy deep into the dermis, stimulating collagen regeneration at the cellular level — a next-generation rejuvenation treatment that revitalizes the skin from within.

  • Mccoom
    ¥ 66,000 (tax included)
  • Conditioned Media Add-on
    ¥ 110,800 (tax included)
  • Mccoom + Conditioned Media
    ¥ 143,800 (tax included)

Downtime:Mild redness or swelling may last from a few hours to several days (varies by individual).Basic aftercare (moisturizing and UV protection) is recommended.Indications and possible side effects will be carefully explained during consultation.

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背景

Advanced Lift-Up Treatment

Gravity-defying rejuvenation for aging skin.
DENSITY offers a medical-grade lift-up therapy that restores refined youthfulness by regenerating skin at the cellular level.This next-generation treatment improves elasticity and tone — not just superficially, but fundamentally — helping you achieve timeless beauty and firmness with confidence.

[Expected Benefits]

Improves sagging / Reduces fine lines / Enhances skin texture

Cheeks + Under Jaw ・・・ ¥ 66,000 (tax included)
Under Eyes ・・・ ¥ 22,000 (tax included)

Downtime:Mild redness or swelling may last from a few hours to several days (varies by individual).Proper moisturizing and UV protection are recommended.Indications and side effects will be explained during consultation.

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医療機器
背景

For pigmentation, melasma, open pores, acne scars, and tattoo removal.

Whether pigmentation, melasma, enlarged pores, acne scars — or even tattoos —the PICO LASER precisely targets problem areas in picoseconds, minimizing unnecessary heat damage while gently breaking down melanin.Experience a clearer, smoother complexion with shorter downtime — the perfect balance of efficacy and gentleness for your skin.

  • Pico Toning
    (Pigmentation, Melasma, Dullness) ・・・¥ 11,000 (tax included)

  • Pico Fusion
    (Freckles, Brightening, Firmness, Pores) ・・・¥ 22,000 (tax included)

  • Pico Spot
    (Up to 5mm) ・・・¥ 11,000 (tax included)

  • per additional 5mm ・・・+¥5,500 (tax included)

Downtime:Mild redness or swelling may last from a few hours to several days (varies by individual).Aftercare such as moisturizing and UV protection is recommended.All indications and potential side effects will be explained during consultation.

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TREATMENT
PROCESS

Treatment Process

1. Consultation (medical history & current medications)

Your treatment plan is determined through an individual consultation. Our specialists carefully review your symptoms and goals, then propose the most appropriate plan tailored to you.

2. Adipose (fat) harvesting — local anesthesia, short procedure

A small amount of fat is collected from the abdomen under local anesthesia by a specialist. The procedure takes about 10 minutes. The incision is approximately 3 mm and is designed to minimize visible scarring.

3. Cell culture (3–4 weeks)

In our in-house Cell Processing Facility (CPF), adipose-derived stem cells are isolated and expanded. To ensure fresh, high-quality cells, the first culture typically requires about 5 weeks; subsequent cultures generally take about 2 weeks.

4. Quality & safety testing

We perform genomic analysis of the cultured stem cells using next-generation sequencing. Only cells that meet safety and quality standards equivalent to Class I under Japan’s Act on the Safety of Regenerative Medicine are provided.

5. Administration (intravenous / local) — outpatient

Depending on the clinical goal, stem cells are administered via IV infusion or local injection. In accordance with the registered Regenerative Medicine Provision Plan, board-certified specialists and regenerative medicine–certified physicians maintain rigorous safety management throughout treatment. After brief observation, you may return home the same day.

◎Safety Framework

Aseptic technique & lot control within our CPF
All cell handling follows strict aseptic procedures with comprehensive lot management in our in-house CPF. Physicians determine indication and dosing based on your condition to balance safety and efficacy. Standardized protocols are in place for any adverse events.

◎Potential Complications

Related to adipose tissue harvesting
Bleeding, subcutaneous bleeding, incisional pain, swelling, infection, skin dimpling, scarring or keloid formation.Rarely: anemia, hematoma, abdominal muscle injury, peritonitis, or anaphylactic reactions have been reported.

Related to stem cell administration
Pain at the injection site; rarely, anaphylactic reactions or pulmonary embolism may occur.

Other unforeseen complications may also occur.

◎Precautions

Please consult a physician in advance if any of the following apply:
・Pregnancy or breastfeeding
・Severe underlying medical conditions
・History of cancer

We will assess each patient’s condition individually and explain safety considerations and indications in detail.

The cell clinic
1F Noah Building, 3-2-12 Akasaka, Minato-ku, Tokyo, Japan
Appointment / Consultation
tel
+81-3-5544-8200
Make an Appointment
Contact Us
Clinic Hours:10:00−18:00 Closed:Saturdays,Sundays,and Year-end/New Year holidays
Orthopedic Specialized Outpatient Clinic:Wednesday afternoons (1st,3rd,and 5th weeks)
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